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Seasonal affective disorder
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===Other treatments=== Depending upon the patient, one treatment (e.g., lightbox) may be used in conjunction with another (e.g., medication).<ref name = "Lam"/> [[Air ioniser|Negative air ionization]], which involves releasing charged particles into the sleep environment, has been found effective, with a 47.9% improvement if the negative ions are in sufficient density (quantity).<ref name="Terman" /><ref name="doi 10.1001/archpsyc.55.10.875">{{cite journal | vauthors = Terman M, Terman JS, Ross DC | title = A controlled trial of timed bright light and negative air ionization for treatment of winter depression | journal = Archives of General Psychiatry | volume = 55 | issue = 10 | pages = 875–82 | date = October 1998 | pmid = 9783557 | doi = 10.1001/archpsyc.55.10.875 | s2cid = 18127922 | doi-access = }}</ref><ref name="ReferenceA">{{cite journal | vauthors = Terman M, Terman JS | title = Treatment of seasonal affective disorder with a high-output negative ionizer | journal = Journal of Alternative and Complementary Medicine | volume = 1 | issue = 1 | pages = 87–92 | date = January 1995 | pmid = 9395604 | doi = 10.1089/acm.1995.1.87 }}</ref> [[Exercise|Physical exercise]] has shown to be an effective form of depression therapy, particularly when in addition to another form of treatment for SAD.<ref>{{cite journal | vauthors = Pinchasov BB, Shurgaja AM, Grischin OV, Putilov AA | title = Mood and energy regulation in seasonal and non-seasonal depression before and after midday treatment with physical exercise or bright light | journal = Psychiatry Research | volume = 94 | issue = 1 | pages = 29–42 | date = April 2000 | pmid = 10788675 | doi = 10.1016/S0165-1781(00)00138-4 | s2cid = 12731381 }}</ref> One particular study noted marked effectiveness for treatment of depressive symptoms, when combining regular exercise with bright light therapy.<ref>{{cite journal | vauthors = Leppämäki S, Partonen T, Lönnqvist J | title = Bright-light exposure combined with physical exercise elevates mood | journal = Journal of Affective Disorders | volume = 72 | issue = 2 | pages = 139–44 | date = November 2002 | pmid = 12200204 | doi = 10.1016/S0165-0327(01)00417-7 }}</ref> Patients exposed to exercise which had been added to their treatments in 20 minutes intervals on the aerobic bike during the day, along with the same amount of time underneath the [[Ultraviolet|UV light]] were seen to make a quick recovery.<ref>{{cite journal | vauthors = Roecklein KA, Rohan KJ | title = Seasonal affective disorder: an overview and update | journal = Psychiatry | volume = 2 | issue = 1 | pages = 20–6 | date = January 2005 | pmid = 21179639 | pmc = 3004726 }}</ref> Of all the psychological therapies aimed at the prevention of SAD, cognitive-behavior therapy, typically involving thought records, activity schedules and a positive data log, has been the subject of the most empirical work. However, evidence for cognitive behavioral therapy or any of the psychological therapies aimed at preventing SAD remains inconclusive.<ref>{{Cite journal |last1=Forneris |first1=Catherine A. |last2=Nussbaumer-Streit |first2=Barbara |last3=Morgan |first3=Laura C. |last4=Greenblatt |first4=Amy |last5=Van Noord |first5=Megan G. |last6=Gaynes |first6=Bradley N. |last7=Wipplinger |first7=Jörg |last8=Lux |first8=Linda J. |last9=Winkler |first9=Dietmar |last10=Gartlehner |first10=Gerald |date=2019-05-24 |title=Psychological therapies for preventing seasonal affective disorder |journal=The Cochrane Database of Systematic Reviews |volume=2019 |issue=5 |pages=CD011270 |doi=10.1002/14651858.CD011270.pub3 |issn=1469-493X |pmc=6533196 |pmid=31124141}}</ref>
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