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===Treatment of stings=== Stings from a Portuguese man o' war can result in severe [[dermatitis]] characterized by long, thin, open wounds that resemble those caused by a whip.<ref>{{cite web|url=http://www.medicinenet.com/image-collection/portuguese_man_of_war_sting_picture/picture.htm|title=Image Collection: Bites and Infestations: 26. Picture of Portuguese Man of War Sting|website=www.medicinenet.com|publisher=MedicineNet Inc |quote=The sting of the Portuguese man-of-war. One of the most painful effects on skin is the consequence of attack by oceanic hydrozoans known as Portuguese men-of-war, which are amazing for their size, brilliant color, and power to induce whealing. They have a small float that buoys them up and from which hang long tentacles. The wrap of these tentacles results in linear stripes, which look like whiplashes, caused not by the force of their sting but from deposition of [[proteolytic]] venom toxins, [[urticariogenic]] and irritant substances.|archive-url=https://web.archive.org/web/20180603114215/https://www.medicinenet.com/image-collection/portuguese_man_of_war_sting_picture/picture.htm |archive-date=2018-06-03 |access-date=2014-06-13}}</ref> These are not caused by any impact or cutting action, but by irritating [[Hives|urticariogenic]] substances in the tentacles.<ref name=James2006>{{cite book |last1=James |first1=William D. |last2=Berger |first2=Timothy G. |first3=Dirk M. |last3=Elston |first4=Richard B. |last4=Odom |title=Andrews' Diseases of the Skin: Clinical Dermatology |url=https://archive.org/details/andrewsdiseasess00mdwi_659 |url-access=limited |publisher=Saunders Elsevier|year=2006 |page=[https://archive.org/details/andrewsdiseasess00mdwi_659/page/n439 429] |isbn=978-0-7216-2921-6}}</ref><ref name="Bolognia">{{cite book |last1=Rapini |first1=Ronald P. |last2=Bolognia |first2=Jean L.|last3=Jorizzo|first3=Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1}}</ref> Treatment for sting pain is immersion in {{convert|45|C}} water for 20 minutes.<ref name=Loten2006>{{cite journal|last1=Loten|first1=Conrad|last2=Stokes|first2=Barrie|last3=Worsley|first3=David|last4=Seymour|first4=Jamie E.|last5=Jiang|first5=Simon|last6=Isbister|first6=Geoffrey K.|title=A randomised controlled trial of hot water (45 Β°C) immersion versus ice packs for pain relief in bluebottle stings|journal=Medical Journal of Australia|volume=184|issue=7|pages=329β333|year=2006|doi=10.5694/j.1326-5377.2006.tb00265.x|pmid=16584366|s2cid=14684627|url=https://www.mja.com.au/system/files/issues/184_07_030406/lot11135_fm.pdf}}</ref> The [[cnidocyte]] found in the [[box jellyfish]] react differently than the [[nematocyst]] in the Portuguese man o' war; cnidocytes are inhibited by application of [[vinegar]], but nematocysts can discharge more venom if vinegar is applied.<ref name=Galsziou2013>{{cite journal|last1=Galsziou|first1=Paul T.|last2=Bennett|first2=John|last3=Greenberg|first3=Peter|last4=Green|first4=Sally|title=Hot water immersion for bluebottle stings|journal=Australian Family Physician|volume=42|issue=6|year=2013|url=https://www.racgp.org.au/getattachment/572969cd-e853-42a6-8392-653145b96a1b/Bluebottle-stings.aspx}}</ref>
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