Editing Norovirus (section)

== Diagnosis ==
Specific diagnosis of norovirus is routinely made by [[polymerase chain reaction]] (PCR) assays or [[quantitative PCR]] assays, which give results within a few hours. These assays are very [[Sensitivity and specificity|sensitive]] and can detect as few as 10 virus particles.<ref name="pmid17175887">{{cite journal |vauthors=Marshall JA, Bruggink LD | title = Laboratory diagnosis of norovirus | journal = [[Clinical Laboratory|Clin. Lab.]] | volume = 52 | issue = 11–12 | pages = 571–81 | year = 2006 | pmid = 17175887 }}</ref>
Tests such as [[ELISA]] that use [[antibody|antibodies]] against a mixture of norovirus strains are available commercially, but lack specificity and sensitivity.<ref name="pmid17391396">{{cite journal | vauthors = Wilhelmi de Cal I, Revilla A, del Alamo JM, Román E, Moreno S, Sánchez-Fauquier A | title = Evaluation of two commercial enzyme immunoassays for the detection of norovirus in faecal samples from hospitalised children with sporadic acute gastroenteritis | journal = Clin. Microbiol. Infect. | volume = 13 | issue = 3 | pages = 341–3 | year = 2007 | pmid = 17391396 | doi = 10.1111/j.1469-0691.2006.01594.x | doi-access = free }}</ref>