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=== Obesity and type 2 Diabetes === Constant disruption caused by chronic jet lag can cause complications to the daily metabolic cycle of an individual due to a hinted link between circadian rhythm and [[Metabolism|metabolic]]/epigenetic mechanisms.<ref>{{cite journal |last1=Stenvers |first1=Dirk Jan |last2=Scheer |first2=Frank A. J. L. |last3=Schrauwen |first3=Patrick |last4=la Fleur |first4=Susanne E. |last5=Kalsbeek |first5=Andries |title=Circadian clocks and insulin resistance |journal=Nature Reviews Endocrinology |date=February 2019 |volume=15 |issue=2 |pages=75β89 |doi=10.1038/s41574-018-0122-1 |pmid=30531917 |url=https://cris.maastrichtuniversity.nl/en/publications/f3ec1de0-8a94-4aac-b6f8-ec8d96e82b5b |hdl=20.500.11755/fdb8d77a-70e3-4ab7-a041-20b2303b418b |hdl-access=free }}</ref> This is due to the process of food intake acting as a [[Zeitgeber]] towards the circadian mechanisms and their control on the metabolic systems. The multiple disruptions of the circadian clock due to chronic jet lag alter eating habits causing irregular eating times, over/under eating, and metabolic inconsistencies that lead to a higher risk of [[type 2 diabetes]] and obesity.<ref>{{cite journal |last1=Sato |first1=Tomoki |last2=Sato |first2=Shogo |title=Circadian Regulation of Metabolism: Commitment to Health and Diseases |journal=Endocrinology |date=6 June 2023 |volume=164 |issue=7 |doi=10.1210/endocr/bqad086 |pmid=37253106 }}</ref>
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