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===Diet=== Diet modification is often recommended as a first-line method of self-treatment for interstitial cystitis, though rigorous controlled studies examining the impact diet has on interstitial cystitis signs and symptoms are currently lacking.<ref name=pmid23276554/> An increase in fiber intake may alleviate symptoms.<ref>{{cite web |title=How to get more fiber in your diet |url=https://www.health.harvard.edu/staying-healthy/how-to-get-more-fiber-in-your-diet |website=Harvard Health |publisher=Harvard Health Publishing |access-date=5 January 2022 |language=en |date=20 May 2021}}</ref> Individuals with interstitial cystitis often experience an increase in symptoms when they consume certain foods and beverages. Avoidance of these potential trigger foods and beverages such as tomatoes, cranberries, caffeine-containing beverages including coffee, tea, and soda, [[alcoholic beverages]], [[chocolate]], [[citrus fruits]], [[Chili pepper|hot peppers]], and [[artificial sweeteners]] may be helpful in alleviating symptoms.<ref name=PMHT0025484/><ref name=pmid19808225/> Diet triggers vary between individuals with IC;<ref name=pmid23276554/> the best way for a person to discover his or her own triggers is to use an [[elimination diet]]. Sensitivity to trigger foods may be reduced if [[Calcium glycerylphosphate|calcium glycerophosphate]] and/or sodium bicarbonate is consumed.<ref>{{cite journal|last1=Friedlander |first1=JI |last2=Shorter |first2=B|last3=Moldwin|first3=RM |title=Diet and its role in interstitial cystitis /bladder pain syndrome (IC/BPS) and comorbid conditions|journal=BJU International|volume=109 |issue=11 |pages=1584β1591 |year=2012 |pmid=22233286 |doi=10.1111/j.1464-410X.2011.10860.x|s2cid=205546249 }}</ref> The foundation of therapy is a modification of diet to help people avoid those foods which can further irritate the damaged bladder wall.<ref>{{Cite journal |last1=Gordon |first1=Barbara |last2=Shorter |first2=Barbara |last3=Sarcona |first3=Alessandra |last4=Moldwin |first4=Robert M. |date=September 2015 |title=Nutritional Considerations for Patients with Interstitial Cystitis/Bladder Pain Syndrome |url=http://dx.doi.org/10.1016/j.jand.2015.03.021 |journal=Journal of the Academy of Nutrition and Dietetics |volume=115 |issue=9 |pages=1372β1379 |doi=10.1016/j.jand.2015.03.021 |pmid=25934323 |issn=2212-2672}}</ref> The mechanism by which dietary modification benefits people with IC is unclear. Integration of neural signals from pelvic organs may mediate the effects of diet on symptoms of IC.<ref name="Klumpp-2008">{{cite journal |last1=Klumpp |first1=David J |last2=Rudick |first2=Charles N |title=Summation model of pelvic pain in interstitial cystitis |journal=Nature Clinical Practice Urology |volume=5 |issue=9 |pages=494β500 |year=2008 |pmid=18769376 |doi=10.1038/ncpuro1203|s2cid=22431404 }}</ref>
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