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=== Genetics === Several genetic loci have been identified as associated with insulin insensitivity. These include variations in loci near the NAT2, GCKR, and IGFI genes, which are linked to insulin resistance. Further research has indicated that loci near these genes are correlated with insulin resistance. However, it is estimated that these loci only account for 25β44% of the genetic component of insulin resistance.<ref>{{cite journal | vauthors = Brown AE, Walker M | title = Genetics of Insulin Resistance and the Metabolic Syndrome | journal = Current Cardiology Reports | volume = 18 | issue = 8 | pages = 75 | date = August 2016 | pmid = 27312935 | pmc = 4911377 | doi = 10.1007/s11886-016-0755-4 }}</ref>
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