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=== LIM genes === {{Main|LIM domain}} LIM genes (named after the initial letters of the names of three proteins where the characteristic domain was first identified) encode two 60 amino acid cysteine and histidine-rich LIM domains and a homeodomain. The LIM domains function in protein-protein interactions and can bind zinc molecules. LIM domain proteins are found in both the cytosol and the nucleus. They function in cytoskeletal remodeling, at focal adhesion sites, as scaffolds for protein complexes, and as transcription factors.<ref>{{cite journal | vauthors = Kadrmas JL, Beckerle MC | title = The LIM domain: from the cytoskeleton to the nucleus | journal = Nature Reviews Molecular Cell Biology | volume = 5 | issue = 11 | pages = 920β31 | date = November 2004 | pmid = 15520811 | doi = 10.1038/nrm1499 | s2cid = 6030950 }}</ref>
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