Editing Flunitrazepam (section)

==Detection==
As of 2016, blood tests can identify flunitrazepam at concentrations of as low as 4&nbsp;nanograms per millilitre; the elimination half life of the drug is 4–12 hours. For urine samples, metabolites can be identified for 60 hours to 28 days, depending on the dose and analytical method used. Hair and saliva can also be analyzed; hair is useful when a long time has transpired since ingestion, and saliva for workplace drug tests.<ref name=Kiss2016/>

Flunitrazepam can be measured in blood or plasma to confirm a diagnosis of poisoning in hospitalized patients, provide evidence in an impaired driving arrest, or assist in a medicolegal death investigation. Blood or plasma flunitrazepam concentrations are usually in a range of 5–20 μg/L in persons receiving the drug therapeutically as a nighttime hypnotic, 10–50 μg/L in those arrested for impaired driving and 100–1000 μg/L in victims of acute fatal overdosage. Urine is often the preferred specimen for routine substance use monitoring purposes. The presence of 7-aminoflunitrazepam, a pharmacologically active metabolite and ''in vitro'' degradation product, is useful for confirmation of flunitrazepam ingestion. In postmortem specimens, the parent drug may have been entirely degraded over time to 7-aminoflunitrazepam.<ref name="pmid17417081">{{cite journal | vauthors = Jones AW, Holmgren A, Kugelberg FC | title = Concentrations of scheduled prescription drugs in blood of impaired drivers: considerations for interpreting the results | journal = Therapeutic Drug Monitoring | volume = 29 | issue = 2 | pages = 248–60 | date = April 2007 | pmid = 17417081 | doi = 10.1097/FTD.0b013e31803d3c04 | s2cid = 25511804 }}</ref><ref name="pmid9456517">{{cite journal | vauthors = Robertson MD, Drummer OH | title = Stability of nitrobenzodiazepines in postmortem blood | journal = Journal of Forensic Sciences | volume = 43 | issue = 1 | pages = 5–8 | date = January 1998 | pmid = 9456517 | doi = 10.1520/JFS16081J}}</ref><ref>{{cite book | vauthors = Baselt R | title = Disposition of Toxic Drugs and Chemicals in Man | edition = 8th | publisher = Biomedical Publications | location = Foster City, CA | date = 2008 | pages = 633–635 }}</ref> Other metabolites include [[desmethylflunitrazepam]] and [[nifoxipam|3-hydroxydesmethylflunitrazepam]].