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===Clinical significance=== ====Anomalies, injuries and diseases==== [[File:Syndactyly type1 hands.jpg|thumb|Radiograph of Type 1 [[Syndactyly]]]] A rare anatomical variation affects 1 in 500 humans, in which the individual has more than the usual number of digits; this is known as [[polydactyly]]. A human may also be born without one or more fingers or underdevelopment of some fingers such as [[symbrachydactyly]]. Extra fingers can be functional. One individual with seven fingers not only used them but claimed that they "gave him some advantages in playing the piano".<ref>{{cite journal | last1 = Dwight | first1 = T | year = 1892 | title = Fusion of hands | journal = Memoirs of the Boston Society of Natural History | volume = 4 | pages = 473β86 }}</ref> [[Phalanx bones|Phalanges]] are commonly fractured. A damaged tendon can cause significant loss of function in fine motor control, such as with a [[mallet finger]]. They can be damaged by cold, including [[frostbite]] and non-freezing cold injury (NFCI); and heat, including [[burn]]s. The fingers are commonly affected by diseases such as [[rheumatoid arthritis]] and [[gout]]. Individuals with diabetes often use the fingers to obtain blood samples for regular blood sugar testing. [[Raynaud's phenomenon]] and [[Paroxysmal hand hematoma]] are neurovascular disorders that affect the fingers. Research has linked the [[Digit ratio|ratio of lengths between the index and ring fingers]] to higher levels of [[testosterone]], and to various [[Digit ratio#Correlation with traits|physical and behavioral traits]] such as penis length<ref name="webmd">{{cite web|url=http://men.webmd.com/news/20110705/study-penis-size-linked-to-length-of-fingers|website=men.webmd.com|title=Penis Size Linked to Length of Fingers |access-date=24 July 2022}}</ref> and risk for development of [[alcohol dependence]]<ref>{{cite journal | last1 = Kornhuber | first1 = J | last2 = Erhard | first2 = G | last3 = Lenz | first3 = B | last4 = Kraus | first4 = T | last5 = Sperling | first5 = W | last6 = Bayerlein | first6 = K | last7 = Biermann | first7 = T | last8 = Stoessel | first8 = C | year = 2011 | title = Low digit ratio 2D:4D in alcohol dependent patients | journal = PLOS ONE | volume = 6 | issue = 4| page = e19332 | doi=10.1371/journal.pone.0019332 | pmid=21547078 | pmc=3081847 | bibcode = 2011PLoSO...619332K| doi-access = free }}</ref> or [[video game addiction]].<ref>{{cite journal | last1 = Kornhuber | first1 = J. | last2 = Zenses | first2 = EM | last3 = Lenz | first3 = B | last4 = Stoessel | first4 = C | last5 = Bouna-Pyrrou | first5 = P | last6 = Rehbein | first6 = F | last7 = Kliem | first7 = S | last8 = MΓΆΓle | first8 = T | year = 2013 | title = Low digit ratio 2D:4D associated with video game addiction | journal = PLOS ONE | volume = 8 | issue = 11| page = e79539 | doi=10.1371/journal.pone.0079539 | pmid=24236143 | pmc=3827365 | bibcode = 2013PLoSO...879539K| doi-access = free }}</ref>
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