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====Cancer==== The evidence for a relation between saturated fat intake and [[cancer]] is significantly weaker, and there does not seem to be a clear medical consensus about it. * Several reviews of [[Case–control study|case–control studies]] have found that saturated fat intake is associated with increased breast cancer risk.<ref>{{cite journal |vauthors=Dandamudi A, Tommie J, Nommsen-Rivers L, Couch S |date=2018|title=Dietary Patterns and Breast Cancer Risk: A Systematic Review|journal=Anticancer Research|volume=38|issue=6|pages=3209–3222|pmid=29848668|doi=10.21873/anticanres.12586|s2cid=44149964|doi-access=free}}</ref><ref>{{cite journal|vauthors=Xia H, Ma S, Wang S, Sun G |year=2015|title=Meta-Analysis of Saturated Fatty Acid Intake and Breast Cancer Risk|journal=Medicine|volume=94|issue=52|pages=e2391|pmid=26717389|doi=10.1097/MD.0000000000002391|pmc=5291630}}</ref><ref>{{cite journal|vauthors=Brennan SF, Woodside JV, Lunny PM, Cardwell CR, Cantwell MM |year=2017|title=Dietary fat and breast cancer mortality: A systematic review and meta-analysis|journal=Critical Reviews in Food Science and Nutrition|volume=57|issue=10|pages=1999–2008|doi=10.1080/10408398.2012.724481|pmid=25692500 |s2cid=34098509 |url=https://pure.qub.ac.uk/en/publications/dietary-fat-and-breast-cancer-mortality-a-systematic-review-and-metaanalysis(d733bb2c-2e38-494e-bb66-03b38759e0c2).html}}</ref> * Another review found limited evidence for a positive relationship between consuming animal fat and incidence of [[colorectal cancer]].<ref name="xxxx2009a" /> * Other meta-analyses found evidence for increased risk of [[ovarian cancer]] by high consumption of saturated fat.<ref name="hunch2001" /> * Some studies have indicated that serum [[myristic acid]]<ref name="mann2003" /><ref name="crowe2008" /> and [[palmitic acid]]<ref name="crowe2008" /> and dietary myristic<ref name="kura2008" /> and palmitic<ref name="kura2008" /> saturated fatty acids and serum palmitic combined with [[tocopherol#Alpha-tocopherol|alpha-tocopherol]] supplementation<ref name="mann2003" /> are [[Prostate cancer#Oils and fatty acids|associated with increased risk]] of [[prostate cancer]] in a dose-dependent manner. These associations may, however, reflect differences in intake or metabolism of these fatty acids between the precancer cases and controls, rather than being an actual cause.<ref name="crowe2008" />
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