Editing Effects of cannabis (section)

=== Onset and duration ===
When smoked, the short-term effects of cannabis manifest within seconds and are fully apparent within a few minutes,<ref name="bjp-ashton">{{cite journal | vauthors = Ashton CH | title = Pharmacology and effects of cannabis: a brief review | journal = The British Journal of Psychiatry | volume = 178 | issue = 2 | pages = 101–6 | date = February 2001 | pmid = 11157422 | doi = 10.1192/bjp.178.2.101 | doi-access = free }}</ref> typically lasting 1–3 hours, varying by the person and the [[Cannabis strain|strain of cannabis]].<ref name="sagov">{{cite web|url=http://www.dasc.sa.gov.au/site/page.cfm?u=128 |title=Cannabis |publisher=Dasc.sa.gov.au |access-date=20 April 2011 |url-status=dead |archive-url=https://web.archive.org/web/20110327053822/http://www.dasc.sa.gov.au/site/page.cfm?u=128 |archive-date=27 March 2011 }}</ref> With oral ingestion, however, the onset of effect is delayed, taking 30 minutes to 2 hours, but the duration is prolonged due to continued slow absorption.<ref name="bjp-ashton" /> The duration of noticeable effects has been observed to diminish after prolonged, repeated use leading to the development of increased tolerance to cannabinoids.<ref>{{Cite journal |last1=Colizzi |first1=Marco |last2=Bhattacharyya |first2=Sagnik |date=October 2018 |title=Cannabis use and the development of tolerance: a systematic review of human evidence |url=https://pubmed.ncbi.nlm.nih.gov/30056176/ |journal=Neuroscience and Biobehavioral Reviews |volume=93 |pages=1–25 |doi=10.1016/j.neubiorev.2018.07.014 |issn=1873-7528 |pmid=30056176 |s2cid=51718458 |access-date=20 December 2022 |archive-date=20 December 2022 |archive-url=https://web.archive.org/web/20221220003736/https://pubmed.ncbi.nlm.nih.gov/30056176/ |url-status=live }}</ref>