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=== Traditional medicine === The main use of anise in traditional European [[herbal medicine]] was for its [[carminative]] effect (reducing [[flatulence]]),{{sfn|Baynes|1878}} as noted by [[John Gerard]] in his ''Great Herball'', an early encyclopedia of herbal medicine: <blockquote>The seed wasteth and consumeth winde, and is good against belchings and upbraidings of the stomach, alaieth gripings of the belly, provoketh urine gently, maketh abundance of milke, and stirreth up bodily lust: it staieth the laske ([[diarrhea]]), and also the white flux ([[leukorrhea]]) in women.<ref name=Gerard>John Gerard, [http://caliban.mpiz-koeln.mpg.de/gerarde/high/IMG_0940.html ''The Herball, or Generall Historie of Plantes''] {{Webarchive|url=https://web.archive.org/web/20110614030203/http://caliban.mpiz-koeln.mpg.de/gerarde/high/IMG_0940.html |date=2011-06-14 }}, 1597, p. 880, side 903</ref></blockquote> According to [[Pliny the Elder]], anise was used as a cure for sleeplessness, chewed with [[alexanders]] and a little [[honey]] in the morning to freshen the breath, and, when mixed with wine, as a remedy for [[asp (reptile)|asp]] bites ([[Natural History (Pliny)|N.H.]] 20.72).<ref>{{cite book|last=Pliny |others=translators John Bostock, Henry Riley |title=The Natural History of Pliny|publisher=Henry Bohn|location=London |year=1856|volume=4|pages=271–274|chapter=Book XX. Anise—sixty-one remedies|oclc=504358830}}</ref> In 19th-century medicine, anise was prepared as ''{{lang|la|aqua anisi}}'' ("Water of Anise") in doses of an ounce or more and as ''{{lang|la|spiritus anisi}}'' ("Spirit of Anise") in doses of 5–20 [[minim (unit)|minim]]s.{{sfn|Chisholm|1911}} In [[Turkey|Turkish]] folk medicine, its seeds have been used as an [[appetite]] stimulant, [[tranquilizer]] or [[diuretic]].<ref>Baytop, T. (1999) ''Therapy with medicinal plants in Turkey, Past and Present.'' Kitapevi, Istanbul, Turkey, 2nd edition, pp. 142.</ref>
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