Editing African clawed frog (section)

=== As transexpression tool ===
''X. laevis'' oocytes are often used as an easy [[model organism|model]] for the artificially induced [[gene expression|expression]] of [[transgene]]s. For example, they are commonly used when studying [[chloroquine resistance]] produced by specialized [[transport protein|transporter]] mutants.<ref name="Wicht-et-al-2020">{{cite journal |last1=Wicht |first1=Kathryn J. |last2=Mok |first2=Sachel |last3=Fidock |first3=David A. |author-link3=David A. Fidock |date=8 September 2020 |title=Molecular Mechanisms of Drug Resistance in ''Plasmodium falciparum'' Malaria |journal=[[Annual Review of Microbiology]] |publisher=[[Annual Reviews (publisher)|Annual Reviews]] |volume=74 |issue=1 |pages=431–454 |doi=10.1146/annurev-micro-020518-115546 |issn=0066-4227 |pmc=8130186 |pmid=32905757}}</ref> Even so the foreign expression tissue may itself confer some alterations to the expression, and so findings may or may not be entirely identical to native expression: For example, iron has been found by Bakouh et al 2017 to be an important substrate for one such transporter in ''X. l.'' oocytes, but {{as of|2020|lc=yes}} iron is merely ''presumptively'' involved in native expression of the same gene.<ref name="Wicht-et-al-2020" />