Editing Vitiligo (section)

== Signs and symptoms ==

The only sign of vitiligo is the presence of pale patchy areas of depigmented skin which tend to occur on the extremities.<ref name="niams">{{cite web |title=What Is Vitiligo? Fast Facts: An Easy-to-Read Series of Publications for the Public Additional |author=National Institute of Arthritis and Musculoskeletal and Skin Diseases |date=March 2007 |url=http://www.niams.nih.gov/Health_Info/Vitiligo/vitiligo_ff.asp#c |access-date=2010-07-18 |url-status=live |archive-url=https://web.archive.org/web/20100715210530/http://www.niams.nih.gov/Health_Info/Vitiligo/vitiligo_ff.asp#c |archive-date=15 July 2010 }}</ref><ref name="halder2">{{cite book |vauthors=Halder RM, Taliaferro S |chapter=72. Vitiligo |veditors=Wolff K, Goldsmith L, Katz S, Gilchrest B, Paller A, Lefell D |title=Fitzpatrick's dermatology in general medicine |edition=7th |location=New York |publisher=McGraw-Hill Professional |year=2007 |isbn=978-0-07-146690-5 |oclc=154751587}}</ref> Some people may experience itching before a new patch appears.<ref name=Whit2015>{{cite journal | vauthors = Whitton ME, Pinart M, Batchelor J, Leonardi-Bee J, González U, Jiyad Z, Eleftheriadou V, Ezzedine K | title = Interventions for vitiligo | journal = The Cochrane Database of Systematic Reviews | volume = 2015 | issue = 2 | pages = CD003263 | date = February 2015 | pmid = 25710794 | pmc = 10887429 | doi = 10.1002/14651858.CD003263.pub5 }}</ref> The patches are initially small, but often grow and change shape.<ref name="niams"/><ref name="halder">{{cite journal | vauthors = Halder RM, Chappell JL | title = Vitiligo update | journal = Seminars in Cutaneous Medicine and Surgery | volume = 28 | issue = 2 | pages = 86–92 | date = June 2009 | pmid = 19608058 | doi = 10.1016/j.sder.2009.04.008 | doi-broken-date = 1 November 2024 }}</ref> When skin [[lesion]]s occur, they are most prominent on the face, hands and wrists.<ref name="niams"/><ref name="halder2"/> The loss of skin pigmentation is particularly noticeable around body orifices, such as the mouth, eyes, [[nostril]]s, [[genitalia]] and [[Navel|umbilicus]].<ref name="niams"/><ref name="halder2"/> Some lesions have [[hyperpigmentation|increased skin pigment]] around the edges.<ref name="huggins">{{cite journal | vauthors = Huggins RH, Schwartz RA, Janniger C | title = Vitiligo | journal = Acta Dermatovenerologica Alpina, Pannonica, et Adriatica | volume = 14 | issue = 4 | pages = 137–42, 144–45 | date = December 2005 | pmid = 16435042 | url = http://www.mf.uni-lj.si/acta-apa/acta-apa-05-4/2.pdf | url-status = live | archive-url = https://web.archive.org/web/20061210104146/http://www.mf.uni-lj.si/acta-apa/acta-apa-05-4/2.pdf | archive-date = 10 December 2006 }}</ref> Those affected by vitiligo who are [[Stigmatization|stigmatized]] for their condition may experience depression and similar [[mood disorder]]s.<ref name="picardi">{{cite journal | vauthors = Picardi A, Pasquini P, Cattaruzza MS, Gaetano P, Melchi CF, Baliva G, Camaioni D, Tiago A, Abeni D, Biondi M | title = Stressful life events, social support, attachment security and alexithymia in vitiligo. A case-control study | journal = Psychotherapy and Psychosomatics | volume = 72 | issue = 3 | pages = 150–158 | year = 2003 | pmid = 12707482 | doi = 10.1159/000069731 | s2cid = 22105282 }}</ref><!-- consider PMID 20616733 here -->
<gallery widths="220" heights="220">
File:Vitiligo03.jpg|Vitiligo on lighter skin
File:Vitiligo1.JPG|Non-segmental vitiligo on dark skin
File:Eyelid vitiligo 06.jpg|Non-segmental vitiligo of the eyelids
</gallery>