Editing Stevens–Johnson syndrome (section)

== Signs and symptoms ==
SJS usually begins with fever, sore throat, and [[Fatigue (medical)|fatigue]], which is commonly misdiagnosed and therefore treated with antibiotics. SJS, SJS/TEN, and TEN are often heralded by fever, sore throat, cough, and burning eyes for 1 to 3 days.<ref name=":0">{{Cite journal|last1=Maverakis|first1=Emanual|last2=Wang|first2=Elizabeth A.|last3=Shinkai|first3=Kanade|last4=Mahasirimongkol|first4=Surakameth|last5=Margolis|first5=David J.|last6=Avigan|first6=Mark|last7=Chung|first7=Wen-Hung|last8=Goldman|first8=Jennifer|last9=Grenade|first9=Lois La|title=Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines|journal=JAMA Dermatology|volume=153|issue=6|pages=587–592|language=en|doi=10.1001/jamadermatol.2017.0160|pmid=28296986|year=2017|s2cid=205110875|url=http://www.zora.uzh.ch/id/eprint/144140/1/LF_2017_Stevens-Johnson_Syndrome_and_Toxic_Necrolysis_Standard_Reporting_and_Evaluation_Guidlines_-_Results_of_a_National_Institutes_of_Health_Working_Group.pdf}}</ref> Patients with these disorders frequently experience burning pain of their skin at the start of disease.<ref name=":0" /> Ulcers and other lesions begin to appear in the mucous membranes, almost always in the mouth and lips, but also in the genital and anal regions. Those in the mouth are usually extremely painful and reduce the patient's ability to eat or drink. [[Conjunctivitis]] occurs in about 30% of children who develop SJS.<ref name="pmid28138822">{{cite journal | vauthors = Adwan MH | title = Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome and the Rheumatologist | journal = Current Rheumatology Reports | volume = 19 | issue = 1 | pages = 3 | date = January 2017 | pmid = 28138822 | doi = 10.1007/s11926-017-0626-z | s2cid = 10549742 }}</ref> A rash of round lesions about an inch across arises on the face, trunk, arms and legs, and soles of the feet, but usually not the scalp.<ref name=Tigchelaar>{{cite web |last1= Tigchelaar |first1= H. |last2= Kannikeswaran |first2= N. |last3= Kamat |first3= D. |title= Stevens–Johnson Syndrome: An intriguing diagnosis |website= pediatricsconsultantlive.com |date= December 2008 |url= http://www.pediatricsconsultantlive.com/display/article/1803329/1403936 |publisher= [[UBM plc|UBM Medica]] |url-access=registration |url-status= live |archive-url= https://web.archive.org/web/20120817000234/http://www.pediatricsconsultantlive.com/display/article/1803329/1403936 |archive-date= August 17, 2012}}</ref>

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File:Mucosal desquamation in a person with Stevens–Johnson syndrome.jpg|Mucosal [[desquamation]] in a person with Stevens–Johnson syndrome
File:Stevens-Johnson Syndrome Conjunctivitis.jpg|[[Conjunctivitis]] in SJS
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