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==Early life, career and research== He was born in [[Des Moines, Iowa]], into a Jewish<ref>{{Cite web |title=Jewish Nobel Prize Winners in Medicine |url=https://www.jinfo.org/Nobels_Medicine.html |access-date=2023-03-30 |website=www.jinfo.org}}</ref> family to Miriam (Spigel) and Lawrence Prusiner, an architect. He spent his childhood in Des Moines and [[Cincinnati]], Ohio, where he attended [[Walnut Hills High School]], where he was known as "the little genius" for his groundbreaking work on a repellent for [[Boxelder bug]]s. Prusiner received a Bachelor of Arts [[Academic degree|degree]] in [[chemistry]] from the [[University of Pennsylvania]] and later received his [[Doctor of Medicine|M.D.]] from the [[University of Pennsylvania School of Medicine]].<ref name="nobelprize"/> Prusiner then completed an [[internship]] in medicine at the University of California, San Francisco. Later Prusiner moved to the [[National Institutes of Health]], where he studied glutaminases in ''[[Escherichia coli|E. coli]]'' in the laboratory of Earl Stadtman.{{cn|date=September 2022}} After three years at NIH, Prusiner returned to UCSF to complete a [[Residency (medicine)|residency]] in [[neurology]]. Upon completion of the residency in 1974, Prusiner joined the faculty of the UCSF neurology department. Since that time, Prusiner has held various faculty and visiting faculty positions at both UCSF and [[University of California, Berkeley|UC Berkeley]].{{cn|date=September 2022}} Since 1999, Prusiner has been director of the Institute for Neurodegenerative Diseases research laboratory at UCSF, working on prion diseases, [[Alzheimer's disease]] and [[tauopathy|tauopathies]].<ref>{{cite web|url=http://prusinerlab.ucsf.edu/people/director.php|title=UCSF β Prusiner Laboratory β Stanley B. Prusiner, M.D.|date=August 28, 2008|access-date=May 9, 2018|url-status=dead|archive-url=https://web.archive.org/web/20080828015629/http://prusinerlab.ucsf.edu/people/director.php|archive-date=August 28, 2008}}</ref>
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