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==Molecular structure== Biochemically, the [[indoleamine]] molecule derives from the amino acid [[tryptophan]], via the (rate-limiting) [[Tryptophan hydroxylase|hydroxylation]] of the 5 position on the ring (forming the intermediate [[5-hydroxytryptophan]]), and then [[Aromatic L-amino acid decarboxylase|decarboxylation]] to produce serotonin.<ref>{{cite journal | vauthors = González-Flores D, Velardo B, Garrido M, et al. | year = 2011 | title = Ingestion of Japanese plums (Prunus salicina Lindl. cv. Crimson Globe) increases the urinary 6-sulfatoxymelatonin and total antioxidant capacity levels in young, middle-aged and elderly humans: Nutritional and functional characterization of their content | url = https://www.researchgate.net/publication/259983119 | journal = Journal of Food and Nutrition Research | volume = 50 | issue = 4| pages = 229–236 }}</ref> Preferable conformations are defined via ethylamine chain, resulting in six different conformations.<ref>{{Cite journal | vauthors = Rychkov DA, Hunter S, Kovalskii VY, Lomzov AA, Pulham CR, Boldyreva EV |date=July 2016 |title=Towards an understanding of crystallization from solution. DFT studies of multi-component serotonin crystals |journal=Computational and Theoretical Chemistry |language=en |volume=1088 |pages=52–61 |doi=10.1016/j.comptc.2016.04.027}}</ref>
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