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==Uses== Mescaline is used [[recreational drug|recreationally]], [[spirituality|spiritually]] (as an [[entheogen]]), and [[medicine|medically]].<ref name="VamvakopoulouNarineCampbell2023" /> It is typically taken [[oral administration|orally]].<ref name="Dinis-OliveiraPereiradaSilva2019" /> ===Dosage=== {{See also|Psychedelic drug#Dosage}} Mescaline is used as a psychedelic at doses of 100 to 1,000{{nbsp}}mg [[oral administration|orally]].<ref name="HolzeSinghLiechti2024" /><ref name="LiechtiHolze2022">{{cite book | vauthors = Liechti ME, Holze F | title = Disruptive Psychopharmacology | chapter = Dosing Psychedelics and MDMA | series = Curr Top Behav Neurosci | volume = 56 | pages = 3β21 | date = 2022 | pmid = 34734392 | doi = 10.1007/7854_2021_270 | isbn = 978-3-031-12183-8 | chapter-url = https://www.researchgate.net/publication/355943062}}</ref><ref name="LuethiLiechti2018">{{cite journal | vauthors = Luethi D, Liechti ME | title = Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics | journal = Int J Neuropsychopharmacol | volume = 21 | issue = 10 | pages = 926β931 | date = October 2018 | pmid = 29850881 | pmc = 6165951 | doi = 10.1093/ijnp/pyy047 }}</ref> Low doses are 100 to 200{{nbsp}}mg, an intermediate or "good effect" dose is 500{{nbsp}}mg, and a high or [[ego dissolution|ego-dissolution]] dose is 1,000{{nbsp}}mg.<ref name="HolzeSinghLiechti2024" /><ref name="LiechtiHolze2022" /> [[Psychedelic microdosing|Microdosing]] involves the use of subthreshold mescaline doses of less than 75{{nbsp}}mg.<ref name="HolzeSinghLiechti2024" /><ref name="LiechtiHolze2022" /> In addition to pure form, mescaline is used in the form of mescaline-containing [[cactus|cacti]] such as [[peyote]] and [[San Pedro cactus (disambiguation)|San Pedro]].
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