Editing Isabella d'Este (section)

== Biography ==
Isabella was born on Tuesday, 19 May 1474 at nine o'clock in the evening.{{sfn|Marek|1976|p=12}} Isabella's mother, [[Eleanor of Naples, Duchess of Ferrara|Eleanor of Naples]], wrote a letter to her friend Barbara Gonzaga describing the details of Isabella's birth<ref>Note: In fifteenth century Italy the day began at sunset rather than at midnight; therefore as Isabella's birth occurred on 19 May at the second hour, this indicated that correctly, she was born on 18 May, at 9.00 P.M.</ref> in [[Ferrara]].{{sfn|Cartwright|1903a}} Eleanor was the daughter of [[Ferdinand I of Naples|Ferdinand I]], the Aragonese King of Naples, and [[Isabella of Clermont]]. {{sfn|Marek|1976|p=12}}

One year later, on 29 June 1475, her sister [[Beatrice d'Este|Beatrice]] was born, and in 1476 and 1477 two brothers, [[Alfonso I d'Este, Duke of Ferrara|Alfonso]] and [[Ferrante d'Este|Ferrante]], were born. In 1479 and 1480 two more brothers were born; [[Ippolito d'Este|Ippolito]] and [[Sigismondo d'Este (1480–1524)|Sigismondo]]. Of all the children born into the family, Isabella is believed to have been the favourite.<ref>{{cite book|last=Gardener |first= Edmund |title= Dukes & Poets in Ferrara |publisher=Archibald Constable & Co. LTD |year= 1904 |location=London |page=238}}</ref>

In the year of her brother Ferrante's birth, Isabella was among the children of the family who travelled to Naples with her mother. When her mother returned to Ferrara, Isabella accompanied her, while the other two children remained in Naples for many years: Beatrice was adopted by her [[Ferdinand I of Naples|grandfather]], and her little brother [[Ferrante d'Este|Ferrante]] was left under the tutelage of their uncle [[Alfonso II of Naples|Alfonso]].<ref>Enrica Guerra, ''Il carteggio tra Beatrice d'Aragona e gli Estensi  (1476–1508)'', pp. 42–43.</ref>
[[File:Giancriostoforo_romano,_medaglia_di_isabella_d'este,_marchesa_di_mantova.JPG|link=https://it.wikipedia.org/wiki/File:Giancriostoforo_romano,_medaglia_di_isabella_d'este,_marchesa_di_mantova.JPG|left|thumb|Medail of Isabella, [[Giovanni Cristoforo Romano]]]]

=== Education ===
Due to her outstanding intellect, she often discussed the classics and the affairs of state with ambassadors. In addition, she was personally acquainted with the painters, musicians, writers, and scholars who lived in and around the court. Besides her extensive knowledge of history and languages, she could also recite [[Virgil]] and [[Terence]] by heart. Isabella was also a talented singer and musician, and was taught to play the [[lute]] by [[Giovanni Angelo Testagrossa]].<ref>{{Cite Grove |last=Ness |first=Arthur J. |title=Giovanni Angelo Testagrossa}}</ref> In addition to these accomplishments, she was also an innovator of new dances, having been instructed in the art of dance by Ambrogio, a Jewish dancing master. {{sfn|Marek|1976|pp=16–17}}

=== Betrothal and marriage ===
[[File:Isabella d'Este palazzo ducale.jpg|thumb|upright|''Ambras Miniature'' of Isabella, anonymous artist (16th century)]]
In 1480, at the age of six, Isabella was betrothed to the eight years older [[Francesco II Gonzaga, Marquess of Mantua|Francesco]], the heir to the Marquess of Mantua. The Duke of Milan requested her hand in marriage for his son, Ludovico, two weeks later. Instead, her sister, [[Beatrice d'Este|Beatrice]] was betrothed to Ludovico and became the Duchess of Milan. Her [[dowry]] amounted to 25,000 [[ducat]]s.<ref name="DBDI">{{cite encyclopedia |url=http://www.treccani.it/enciclopedia/isabella-d-este-marchesa-di-mantova_(Dizionario-Biografico) |title=ISABELLA d'Este, marchesa di Mantova |first=Raffaele |last=Tamalio |encyclopedia=Dizionario Biografico degli Italiani |language=it |volume=62 |year=2004}}</ref> Although he was not handsome, Isabella admired Francesco for his strength and bravery; she also regarded him as a gentleman. After their first few encounters she began to enjoy his company and she spent the next few years getting to know him and preparing to be the Marchioness of Mantua. During their courtship, Isabella treasured the letters, poems, and sonnets he sent her as gifts.{{citation needed|date=February 2019}}

Ten years later, on 11 February 1490, at age 15, she married Francesco [[Proxy marriage|by proxy]]. By then, he had succeeded to the marquisate. Besides being the Marquess, Francesco was captain general of the armies of the [[Republic of Venice]]. Isabella became his wife amid a spectacular outpouring of public rejoicing and a grand celebration that took place on 15 February.<ref name="DBDI" /> She brought the sum of 3,000 ducats as her marriage portion, as well as valuable jewelry, dishes, and a silver service. {{sfn|Marek|1976|p=28}} Prior to the magnificent banquet which followed the wedding ceremony, Isabella rode through the main streets of Ferrara astride a horse draped in gems and gold. {{sfn|Marek|1976|p=30}}

==== Relations with Milan ====
In 1491 Isabella went with a small entourage to Brescello and from there to Pavia, to accompany her sister [[Beatrice d'Este|Beatrice]] who was married to [[Ludovico Sforza|Ludovico il Moro]]. On this occasion she saw [[Galeazzo Sanseverino]] again —- as she had known him as a child in Ferrara —- with whom she began a large, and at times humorous, exchange of letters.{{sfn|Cartwright|1945|pp=51–58 }} However, his identity is not certain and could be the almost homonymous Galeazzo Visconti, Count of [[Busto Arsizio]], a courtier also dear to the dukes.<ref name=":7">{{cite book |title=Delle relazioni di Isabella d'Este Gonzaga con Ludovico e Beatrice Sforza|author=Alessandro Luzio|author2=Rodolfo Renier|pages=30–31}}</ref> 
[[File:Statua_di_San_Vittore_dal_basso_museo_del_Duomo_di_Milano.jpg|upright|link=https://it.wikipedia.org/wiki/File:Statua_di_San_Vittore_dal_basso_museo_del_Duomo_di_Milano.jpg|left|thumb|Probable portrait of [[Galeazzo Sanseverino]], statue in the collection of the Great Museum of the Duomo of Milan.]]
Between the two immediately ignited a dispute, destined to last for months, on who was the best paladin, Orlando or Rinaldo: Galeazzo supported the first, the sisters d'Este the second. Galeazzo, who exercised a strong fascination, soon managed to convert them both to Orlando's faith, but Isabella, once back in Mantua, returned to prefer Rinaldo, so that Galeazzo remembered her as "I alone was enough to make her change her mind and cry out ''Rolando! Rolando!''", invited her to follow her sister's example and swore that he would convert her a second time, as soon as they met again. Isabella jokingly replied that she would then bring a frog to offend him, and the dispute went on for a long time.<ref name=":7" />

On 11 February, speaking to her about the amusements he had with Beatrice, he wrote to her: "I will also strive to improve in order to give greater pleasure to the S. V., when I come for her this summer", and lamented the lack of "his sweet company". {{sfn|Luzio|Renier|1890|pp=39–40 }} Isabella's presence was in fact much desired in Milan, not only by Galeazzo but also by her sister, Ludovico and the other courtiers, however the Marquise was able to go there a few times, as her husband Francesco was wary of sending it to her, judging that in that court too many "madness" were committed, and perhaps also out of jealousy of Ludovico.{{sfn|Pizzagalli|2001|p=137}} 
[[File:Beatrice_e_Isabella_d'Este.jpg|link=https://it.wikipedia.org/wiki/File:Beatrice_e_Isabella_d'Este.jpg|thumb|Alleged portrait of the two sisters: [[Beatrice d'Este|Beatrice]] (left) and Isabella (right), in the ceiling fresco of the Sala del Tesoro of Palazzo Costabili near Ferrara. Attributed [[Benvenuto Tisi|Benvenuto Tisi da Garofalo]], dated 1503–1506.]]
Despite the affection, Isabella began to feel envy for her sister Beatrice, first for the very fortunate marriage that had touched her and for the enormous riches, then for the two sons in perfect health who were born to her a short time later, while she seemed unable to have children,{{sfn|Pizzagalli|1999|p=106}}{{sfn|Valeri|1913|p=381}} and in this aroused the concerns of her mother Eleonora, who continually exhorted her in letters to be as close as possible to her husband.<ref>{{Cite web|url=http://www.rm.unina.it/rivista/dwnl/saggi_ferrari_09.pdf|title=Un'educazione sentimentale per lettera: il caso di Isabella d'Este (1490–1493)|access-date=28 September 2021|archive-url=https://web.archive.org/web/20210930075617/http://www.rm.unina.it/rivista/dwnl/saggi_ferrari_09.pdf|archive-date=30 September 2021|url-status=live}}</ref> A certain hatred can also be seen in a letter to his mother dating back to his visit to Pavia in August 1492, when, speaking of Beatrice, he wrote: "she is not a greater than me, but she is much bigger!"; in a similar way she also expressed herself to her husband, not being able yet to know, perhaps, that the sister's coarseness was due to the incipient pregnancy (she was at the fourth-fifth month).{{sfn|Mazzi|2004|pp=38,44–50}} These frictions were perhaps also linked to the fact that Ludovico had initially asked for Isabella's hand, in 1480, and that this had not been possible because, only a few days earlier, Duke Ercole had officially promised it to Francesco Gonzaga. {{sfn|Cartwright|1945|p=7}}

Despite everything, in 1492 she was very close to Beatrice in a difficult moment of her pregnancy, that is when she was suddenly struck by an attack of malarial fevers, and in 1495 she went again to Milan to assist her sister in her second birth and also baptized her nephew Francesco. {{sfn|Luzio|Renier|1890|p=107 }}

In the summer of 1494, on the occasion of the descent of the French into Italy, Beatrice invited her sister to Milan to kiss Gilbert of Montpensier and others of the royal house, according to the custom French. Secretary Benedetto Capilupi reported: {{sfn|Luzio|Renier|1890|p=97 }}{{Blockquote|The Duchess says that when the Duke of Orliens came, she had to dress colorfully, dance and be kissed by the Duke, who wanted to kiss all the bridesmaids and women of account. [...] Coming Count Delfino or someone else of royal blood, the Duchess invites the S.V. to take these little kisses|Benedetto Capilupi's letter to Isabella d'Este}}In fact, it does not seem that Beatrice had any conflicting feelings towards Isabella, nor that she saw with a bad eye the complicity between the latter and her husband Ludovico. The Moro in fact, who was of generous nature, often gave Isabella even very expensive gifts: once he sent her fifteen arms of a fabric so precious as to cost forty ducats on her arm – an amazing sum – saying that he had already made a dress for Beatrice. {{sfn|Luzio|Renier|1890|p=62 }} 
[[File:7580_-_Ludovico_il_Moro_-_Museo_del_Paesaggio_(Verbania)_-_Foto_Giovanni_Dall'Orto,_8-Jan-2012a.jpg|link=https://it.wikipedia.org/wiki/File:7580_-_Ludovico_il_Moro_-_Museo_del_Paesaggio_(Verbania)_-_Foto_Giovanni_Dall'Orto,_8-Jan-2012a.jpg|thumb|[[Ludovico Sforza|Ludovico il Moro]], Isabella's brother-in-law. Round from the Renaissance frieze torn from the Visconti castle of Invorio Inferiore]]
After the death of his wife, which took place in 1497, Ludovico came to allude to a secret relationship with Isabella, claiming that it was out of jealousy of his wife that the Marquis Francesco played a double game between him and the Lordship of Venice. The rumor was however promptly denied by his father Ercole.<ref>Daniela Pizzagalli, La signora del Rinascimento. Vita e splendori di Isabella d'Este alla corte di Mantova, Rizzoli, 2001, p. 137.</ref>

Others instead defined Beatrice's attitude towards her sister as "complexed second child"<ref>{{cite book |title=Lettere ai Gonzaga|url=https://books.google.com/books?id=05eufby9XLkC&dq=cerse&pg=PA426|author=Floriano Dolfo|year = 2002|page=255| publisher=Ed. di Storia e Letteratura |isbn = 9788887114522}}</ref> because in the letter of congratulations to Isabella for the birth of little Eleonora - who, being female, incredibly disappointed her mother - she added the greetings of her little son Hercules to "soa cusina", despite not having the child yet turned one year of age, something that historians such as Luciano Chiappini interpreted as a sort of mockery, of "refined malice", "a slap given with grace and grace". In fact, if Isabella was always the daughter most loved by her parents, Beatrice had been ceded to her grandfather, and only with the birth of the firstborn had she obtained her own revenge.<ref name=":22">{{cite news |title=Gli Estensi|author=Luciano Chiappini|agency=Dall'Oglio|pages=172–173}}</ref>

Other mischief between sisters dates back to the weeks immediately following the battle of Fornovo: Beatrice, who was at the siege of Novara together with the Marquis Francesco, wanted to see the booty stolen from the tent of King Charles VIII during the battle, booty that however Francesco had already sent to his wife in Mantua. He wrote to his wife to give it to his sister-in-law, but Isabella replied that she was not so willing to cede this honor to her sister and, with the excuse that she lacked a mule, begged her husband to invent some expedient. Beatrice replied that it was not her intention to steal the booty from her sister, but that she only wanted to see it all together and then return it to her. Meanwhile, it occurred to her to procure "a femina de partito", that is, a high-ranking prostitute, to Francis, saying to do it "for a good cause and to avoid greater evil", that is to say to preserve her brother-in-law and sister from the terrible malfrancese, but perhaps also to ingratiate herself with him. In October Francis wrote to his wife sorry that she was not there with them to see the army before it was disbanded,<ref>Alessandro Luzio e Rodolfo Renier, Delle relazioni d'Isabella d'Este Gonzaga con Lodovico e Beatrice Sforza, Milano, Tipografia Bortolotti di Giuseppe Prato, 1890, pp. 114-119.</ref> but it does not seem that he had urged her to come, probably because he had at heart his safety (the camps were dangerous places, where violent fights often broke out, and Beatrice herself had been saved on one occasion by Francis, when she risked being raped by a few thousand Alemannic mercenaries).<ref>Deputazione di storia patria per la Lombardia, ''Archivio storico lombardo'', Società storica lombarda, 1874, pp. 348-349.</ref>

Moreover, Isabella had already had a mishap with some Genoese soldiers who, upon entering the city in 1492, surrounded her to appropriate her mount and harness, according to custom. So she later told her husband: "I was never more afraid; and they tore all the harness to pieces, and took off the bridle before I could dismount, despite the fact that the governor interposed him and that I voluntarily offered it to him. I lost heart, although among so many partisans I was afraid of some misfortune. Finally, helped, I freed myself from their hands ".<ref>Alessandro Luzio e Rodolfo Renier, Delle relazioni d'Isabella d'Este Gonzaga con Lodovico e Beatrice Sforza, Milano, Tipografia Bortolotti di Giuseppe Prato, 1890, p. 64.</ref>

Having also received different educations, the two sisters were the opposite of each other: Isabella, more like her mother, was sweet, graceful and a lover of tranquility; Beatrice, more like her father, was impetuous, adventurous and aggressive.{{sfn|de Mazzeri|1986|p=46}} Beatrice loved to shoot [[crossbow]],<ref>Paolo Negri, Studi sulla crisi italiana alla fine del secolo, Archivio storico lombardo: giornale della Società storica lombarda, anno 51, fasc. 1-2 (1924), p. 130.</ref> Isabella had "the hand so light that we cannot play well [the clavichord], when we have to strain it for the hardness of the keys".<ref>Musici alla corte degli Sforza, Archivio storico lombardo, 1887, p. 295.</ref> However, they were united by the desire to excel in everything.<ref name=":22" />

In the last two hundred years historians and writers were divided in preference for one or the other: many - such as [[Francesco Malaguzzi Valeri]] and [[Maria Bellonci]] - regretted that Ludovico had not, only briefly, married Isabella, fantasizing about the splendors that Isabella would be able to bring to Milan, in conditions of greater well-being than to Mantua, and how he could distract the Moro from his perverse policy. These judgments were not separated from a blatant contempt for the second daughter, as in the case of [[Alessandro Luzio]], who writes: "The luck that made play of this Sforza, making him pass from the brightest heights to the darkest abysses of misery, had in April 1480 exchanged a beneficial star for a sinister meteor".<ref>Luzio Alessandro. Isabella d'Este e la corte sforzesca, Archivio Storico Lombardo : Giornale della società storica lombarda (1901 mar, Serie 3, Volume 15, Fascicolo 29), p. 147.</ref>

In truth, other historians, including [[Rodolfo Renier]] himself, Luzio's colleague, judged that Beatrice was the most suitable wife for Ludovico, since she knew, with her own audacity, to instill courage in her insecure consort, and acquired political depth already in her early youth, so much so as to be decisive in situations of greatest danger, while Isabella could boast a role in this sense only in the years of maturity.<ref>''Gaspare Visconti'', Rodolfo Renier, Tip. Bortolotti di Giuseppe Prato, 1886, pp. 6-7.</ref><ref>Strenna Italiana, vol. 19, p. 137.</ref> The different fate of the two sisters certainly weighed in these judgments: Isabella lived sixty-five years, Beatrice died at twenty-one. It was from this tragic loss, for which she proved inconsolable,<ref>Maria Serena Mazzi, Come rose d'inverno, le signore della corte estense nel '400, Nuovecarte, 2004, p. 43.</ref> that Isabella undertook to support her brother-in-law's cause with her husband Francesco, who was against him. So he continued to do until the fall of the Sforza, in 1499, when he suddenly changed sides and declared himself to be "good French".<ref>Daniela Pizzagalli, La signora del Rinascimento. Vita e splendori di Isabella d'Este alla corte di Mantova, Rizzoli, 2001, pp. 135-140.</ref>

==== Marriage ====
As the couple had known and admired one another for many years, their mutual attraction deepened into love. Reportedly, marriage to Francesco caused Isabella to "bloom".{{sfn|Marek|1976|p=33}} At the time of her wedding, Isabella was said to have been pretty, slim, graceful, and well-dressed. {{sfn|Marek|1976|pp=33–34}} Her long, fine hair was dyed a fashionable pale blonde and her eyes were described as "brown as fir cones in autumn, scattered laughter".{{sfn|Marek|1976|p=34}}

Isabella's relationship with her husband over the years often proved to be tense, at times very tense, both for the political differences between the two and for the difficulty in procreating a male heir. In truth, Francesco for his part was always very proud of his daughters and never showed himself disappointed, indeed from the beginning he declared himself in love with the firstborn Eleonora, despite the absolute disappointment of Isabella who refused her daughter, who was then very lovingly educated by her sister-in-law Elisabetta, who because of her husband's impotence never had children. When in 1496 the second daughter Margherita was born, Isabella was so angry that she wrote to her husband, who was then fighting the French in Calabria, a letter in which she blamed him, declaring that she did nothing but reap the fruits of his sown. Francis replied that he was instead very happy with the birth of his daughter – who, however, he did not have time to know, having died in swaddling clothes – and indeed forbade anyone to show discontent with it.{{sfn|Pizzagalli|2001|pp=87–88,114–115}}

Only in 1500 their son [[Federico II Gonzaga, Duke of Mantua|Federico]] was born.{{sfn|Bini|2001|p=13}}

[[File:Francesco II Gonzaga.jpg|thumb|upright|left|Isabella's husband, [[Francesco II Gonzaga, Marquess of Mantua]]]]

In his capacity of captain general of the Venetian armies, Francesco often was required to go to [[Venice]] for conferences that left Isabella in Mantua on her own at ''La Reggia'', the ancient palace that was the [[family seat]] of the Gonzagas.{{sfn|Marek|1976|p=35}} She did not lack company, however, as she passed the time with her mother and with her sister, Beatrice. Upon meeting Elisabetta Gonzaga, her 18-year-old sister-in-law, the two women became close friends. They enjoyed reading books, playing cards, and travelling about the countryside together. Once they journeyed as far as [[Lake Garda]] during one of Francesco's absences. {{sfn|Marek|1976|p=35}}

==== Diplomatic missions ====
Isabella had met the French king in Milan in 1500 on a successful diplomatic mission that she had undertaken to protect Mantua from French invasion. Louis had been impressed by her alluring personality and keen intelligence. {{sfn|Marek|1976|pp=80–81}} It was while she was being entertained by Louis, whose troops occupied Milan, that she offered asylum to Milanese refugees including [[Cecilia Gallerani]], the refined mistress of her sister Beatrice's husband, [[Ludovico Sforza]], Duke of Milan, who had been forced to leave his duchy in the wake of French occupation. Isabella presented Cecilia to King Louis, describing her as a "lady of rare gifts and charm".{{sfn|Marek|1976|p=80}}

==== Lucrezia Borgia ====
A year after her 1502 marriage to Isabella's brother Alfonso, the notorious [[Lucrezia Borgia]] became the mistress of Francesco.<ref>Note:In June 1505, Alfonso succeeded their father as duke, making Lucrezia Duchess of Ferrara</ref> At about the same time, Isabella had given birth to a daughter, Ippolita, and she continued to bear him children throughout Francesco and Lucrezia's long, passionate affair, which was more sexual than romantic.{{sfn|Marek|1976|pp=166–69}} Lucrezia had previously made overtures of friendship to Isabella which the latter had coldly and disdainfully ignored. From the time Lucrezia had first arrived in Ferrara as Alfonso's intended bride, Isabella, despite having acted as hostess during the wedding festivities, had regarded Lucrezia as a rival, whom she sought to outdo at every opportunity. {{sfn|Marek|1976|pp=147–48}} Francesco's affair with Lucrezia, whose beauty was renowned,{{sfn|Marek|1976|p=33}} caused Isabella much jealous suffering and emotional pain.{{sfn|Marek|1976|pp=166–69}} The liaison ended when he contracted [[syphilis]] as a result of encounters with prostitutes.{{citation needed|date=February 2021}}

=== Regency ===
[[File:Leonardo da Vinci, Portrait of Isabella d'Este.jpg|left|thumb|[[Portrait of Isabella d'Este (Leonardo)|Portrait of Isabella d'Este]] by [[Leonardo da Vinci]] (1499–1500)]]
Isabella played an important role in Mantua during troubled times for the city. When her husband was captured in 1509 and held hostage in Venice, she took control of Mantua's military forces and held off the invaders until his release in 1512. In the same year, 1512, she was the hostess at the Congress of Mantua, which was held to settle questions concerning Florence and Milan. {{sfn|Marek|1976|p=250}} As a ruler, she appeared to have been much more assertive and competent than her husband. When apprised of this fact upon his return, Francesco was furious and humiliated at being surpassed by his wife's superior political ability. This caused their marriage to break down irrevocably. As a result, Isabella began to travel freely and live independently from her husband until his death on 19 March 1519.<ref>{{Cite web |title=Brooklyn Museum: Isabella d'Este |url=https://www.brooklynmuseum.org/eascfa/dinner_party/place_settings/isabella_d_este |access-date=5 December 2022 |website=www.brooklynmuseum.org}}</ref>

After the death of her husband, Isabella ruled Mantua as regent for her son [[Frederick II, Duke of Mantua|Federico]]. She began to play an increasingly important role in Italian politics, steadily advancing Mantua's position. She was instrumental in promoting Mantua to a Duchy, which was obtained by wise diplomatic use of her son's marriage contracts. She also succeeded in obtaining a [[Cardinal (Catholicism)|cardinal]]ate for her son [[Ercole Gonzaga|Ercole]]. She further displayed shrewd political acumen in her negotiations with [[Cesare Borgia]], who had dispossessed [[Guidobaldo da Montefeltro]], [[duke of Urbino]], the husband of her sister-in-law and good friend [[Elisabetta Gonzaga]] in 1502.{{citation needed|date=February 2024}}

=== Widowhood ===

==== "Devoted head of state" ====
As a widow, Isabella at the age of 45 became a "devoted head of state". {{sfn|Marek|1976|p=204}} Her position as a Marquise required her serious attention, therefore she was required to study the problems faced by a ruler of a city-state. To improve the well-being of her subjects she studied architecture, agriculture, and industry, and followed the principles that [[Niccolò Machiavelli]] had set forth for rulers in his book ''[[The Prince]]''. In return, the people of Mantua respected and loved her. {{sfn|Marek|1976|p=205}}

[[File:BLW Plate with Hippolytus and Phaedra.jpg|thumb|[[Maiolica]] plate from [[Urbino]] with the arms of Isabella and her late husband, c. 1524 ([[Victoria and Albert Museum]])]]
Isabella left Mantua for Rome in 1527. She was present during the catastrophic [[Sack of Rome (1527)|Sack of Rome]], when she converted her house the ''Palazzo Colonna'', into an asylum for approximately 2,000 people (including clerics, nobles and common citizens) fleeing the Imperial soldiers. Her huge palace was the only place safe from attacks, because her son Ferrante Gonzaga was a general in the invading army and she herself had good relationship with the emperor. When she left Rome, she managed to acquire safe passage for all the refugees who had sought refuge in her home.<ref>{{cite book |last1=Bartlett |first1=Kenneth |title=The Renaissance in Italy: A History |date=15 November 2019 |publisher=Hackett Publishing |isbn=978-1-62466-820-3 |page=315 |url=https://books.google.com/books?id=3ta-DwAAQBAJ&pg=PA315 |access-date=5 September 2022 |language=en}}</ref><ref>{{cite book |last1=Wagner |first1=John A. |title=Voices of the Renaissance: Contemporary Accounts of Daily Life |date=4 February 2022 |publisher=ABC-CLIO |isbn=978-1-4408-7604-2 |page=137 |url=https://books.google.com/books?id=O3FYEAAAQBAJ&pg=PA137 |access-date=5 September 2022 |language=en}}</ref>

==== Later years and death ====
Once Rome became stabilized following the sacking, she left the city and returned to Mantua. She made it a centre of culture, started a school for girls, and turned her ducal apartments into a museum containing the finest art treasures. This was not enough to satisfy Isabella, already in her mid-sixties, so she returned to political life and ruled [[Solarolo]], in [[Emilia-Romagna|Romagna]] until her death on 13 February 1539. She was buried beside her husband in the Church of Santa Paola in Mantua, but the remains were stolen.<ref>{{Cite web |last=Canadè |first=Rossella |title=Dalle ossa riesumate l'altra faccia dei Gonzaga |url=http://gazzettadimantova.gelocal.it/cronaca/2011/02/06/news/dalle-ossa-riesumate-l-altra-faccia-dei-gonzaga-1.148964|archive-url=https://web.archive.org/web/20140429050046/http://gazzettadimantova.gelocal.it/cronaca/2011/02/06/news/dalle-ossa-riesumate-l-altra-faccia-dei-gonzaga-1.148964 |archive-date=29 April 2014 }}</ref><ref>{{Cite web|title=Este, Beatrice d' and Isabella d' – Dictionary definition of Este, Beatrice d' and Isabella d' {{!}} Encyclopedia.com: FREE online dictionary|url=http://www.encyclopedia.com/women/encyclopedias-almanacs-transcripts-and-maps/este-beatrice-d-and-isabella-d|access-date=1 February 2018|website=www.encyclopedia.com}}</ref>