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==History== The term was introduced by [[Rudolf von Kölliker]] in 1863, originally as a synonym for [[protoplasm]], but later it has come to mean the cell substance and organelles outside the nucleus.<ref>{{Cite book |last=von Kölliker |first=Rudolf |title=Handbuch der Gewebelehre des Menschen |date=1863 |publisher=Wilhelm Engelmann |location=Leipzig |chapter=4. Auflage |chapter-url=https://books.google.com/books?id=5mtARc4NAi0C |name-list-style=vanc}}</ref><ref>{{Cite book |url=https://books.google.com/books?id=Ian_AwAAQBAJ |title=Dictionary of the history of science |vauthors=Bynum WF, Browne EJ, Porter R |date=1981 |isbn=9781400853410 |location=Princeton University Press}}</ref> There has been certain disagreement on the definition of cytoplasm, as some authors prefer to exclude from it some organelles, especially the [[vacuole]]s<ref>{{Cite book |title=Water deficits and plant growth, Vol. III. Plant responses and control of water balance. |vauthors=Parker J |date=1972 |publisher=Academic Press |isbn=9780323153010 |veditors=Kozlowski TT |location=New York |pages=125–176 |chapter=Protoplasmic resistance to water deficits |chapter-url=https://books.google.com/books?id=gOEr2alLRUYC}}</ref> and sometimes the plastids.<ref>{{Cite journal |vauthors=Strasburger E |year=1882 |title=Ueber den Theilungsvorgang der Zellkerne und das Verhältnis der Kernteilung zur Zellteilung |url=https://www.biodiversitylibrary.org/item/49525#page/536/mode/1up |url-status=live |journal=Arch Mikr Anat |volume=21 |pages=476–590 |doi=10.1007/BF02952628 |s2cid=85233009 |archive-url=https://web.archive.org/web/20170827124018/http://www.biodiversitylibrary.org/item/49525#page/536/mode/1up |archive-date=27 August 2017 |hdl-access=free |hdl=2027/hvd.32044106199177}}</ref>
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