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==Signs and symptoms== [[File:Depiction of a person suffering from Coronary Artery Disease.png| thumb|220x124px | right |Illustration of someone suffering coronary artery disease]] The most common symptom is [[chest pain]] or discomfort that occurs regularly with activity, after eating, or at other predictable times; this phenomenon is termed stable [[angina]] and is associated with [[stenosis|narrowing]] of the [[artery|arteries]] of the [[heart]]. Angina also includes chest tightness, heaviness, pressure, numbness, fullness, or squeezing.<ref name="Cleveland Clinic">{{cite web |title=Coronary Artery Disease Symptoms: Types, Causes, Risks, Treatment |url=https://my.clevelandclinic.org/health/symptoms/16821-coronary-artery-disease-symptoms |website=Cleveland Clinic }}</ref> Angina that changes in intensity, character, or frequency is termed unstable. [[Unstable angina]] may precede [[myocardial infarction]]. In adults who go to the emergency department with an unclear cause of pain, about 30% have pain due to coronary artery disease.<ref>{{cite journal | vauthors = Kontos MC, Diercks DB, Kirk JD | title = Emergency department and office-based evaluation of patients with chest pain | journal = Mayo Clinic Proceedings | volume = 85 | issue = 3 | pages = 284β99 | date = March 2010 | pmid = 20194155 | pmc = 2843115 | doi = 10.4065/mcp.2009.0560 }}</ref> Angina, shortness of breath, sweating, nausea or vomiting, and lightheadedness are signs of a heart attack or myocardial infarction, and immediate emergency medical services are crucial.<ref name="Cleveland Clinic" /> With advanced disease, the narrowing of coronary arteries reduces the supply of oxygen-rich blood flowing to the heart, which becomes more pronounced during strenuous activities during which the heart beats faster and has an increased oxygen demand.<ref>{{Cite web|title=Coronary artery disease β Symptoms and causes|url=https://www.mayoclinic.org/diseases-conditions/coronary-artery-disease/symptoms-causes/syc-20350613|access-date=2020-06-27|website=Mayo Clinic|language=en}}</ref> For some, this causes severe symptoms, while others experience no symptoms at all.<ref name="HLB2014" /> === Symptoms in females === {{Further|Cardiovascular disease in women}} Symptoms in females can differ from those in males, and the most common symptom reported by females of all races is shortness of breath.<ref>{{cite journal | vauthors = McSweeney JC, O'Sullivan P, Cleves MA, Lefler LL, Cody M, Moser DK, Dunn K, Kovacs M, Crane PB, Ramer L, Messmer PR, Garvin BJ, Zhao W | display-authors = 6 | title = Racial differences in women's prodromal and acute symptoms of myocardial infarction | journal = American Journal of Critical Care | volume = 19 | issue = 1 | pages = 63β73 | date = January 2010 | pmid = 20045850 | pmc = 2860802 | doi = 10.4037/ajcc2010372 }}</ref> Other symptoms more commonly reported by females than males are extreme fatigue, sleep disturbances, indigestion, and anxiety.<ref name="McSweeney-2003">{{cite journal | vauthors = McSweeney JC, Cody M, O'Sullivan P, Elberson K, Moser DK, Garvin BJ | title = Women's early warning symptoms of acute myocardial infarction | journal = Circulation | volume = 108 | issue = 21 | pages = 2619β23 | date = November 2003 | pmid = 14597589 | doi = 10.1161/01.CIR.0000097116.29625.7C | doi-access = free }}</ref> However, some females experience irregular heartbeat, dizziness, sweating, and nausea.<ref name="Cleveland Clinic" /> Burning, pain, or pressure in the chest or upper abdomen that can travel to the arm or jaw can also be experienced in females, but females less commonly report it than males.<ref name="McSweeney-2003" /> Generally, females experience symptoms 10 years later than males.<ref>{{cite web |title=Women & Cardiovascular Disease |url=https://my.clevelandclinic.org/health/diseases/17645-women--cardiovascular-disease |website=Cleveland Clinic }}</ref> Females are less likely to recognize symptoms and seek treatment.<ref name="Cleveland Clinic"/>
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