Editing Anandamide (section)

== Discovery ==
Anandamide was discovered by [[Raphael Mechoulam]] and fellow coworkers in 1992. This was the first marijuana-like substance produced by the human body to be observed. By examining a pig brain and canine gut, they were able to isolate ANA using [[mass spectrometry]] and [[nuclear magnetic resonance spectroscopy]].<ref>{{cite journal | vauthors = Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R | title = Isolation and structure of a brain constituent that binds to the cannabinoid receptor | journal = Science | volume = 258 | issue = 5090 | pages = 1946–1949 | date = December 1992 | pmid = 1470919 | doi = 10.1126/science.1470919 | bibcode = 1992Sci...258.1946D }}</ref> ANA works within the system of the brain associated with the feeling of reward, and as such, has been the topic of many research studies.<ref>{{cite journal | vauthors = Scherma M, Masia P, Satta V, Fratta W, Fadda P, Tanda G | title = Brain activity of anandamide: a rewarding bliss? | journal = Acta Pharmacologica Sinica | volume = 40 | issue = 3 | pages = 309–323 | date = March 2019 | pmid = 30050084 | pmc = 6460372 | doi = 10.1038/s41401-018-0075-x }}</ref> Since the 1992 findings, many studies have been completed to examine ANA further, including research on behavioral and molecular effects.