Editing Adenosine monophosphate (section)

==Production and degradation==
AMP does not have the high energy [[phosphoanhydride]] bond associated with ADP and ATP. AMP can be produced from [[Adenosine diphosphate|ADP]] by the [[Adenylate kinase|myokinase (adenylate kinase)]] reaction when the ATP reservoir in the cell is low:<ref>{{Cite journal |last1=Baker |first1=Julien S. |last2=McCormick |first2=Marie Clare |last3=Robergs |first3=Robert A. |date=2010 |title=Interaction among Skeletal Muscle Metabolic Energy Systems during Intense Exercise |journal=Journal of Nutrition and Metabolism |volume=2010 |pages=905612 |doi=10.1155/2010/905612 |issn=2090-0732 |pmc=3005844 |pmid=21188163 |doi-access=free }}</ref><ref>{{Citation |last=Valberg |first=Stephanie J. |title=Chapter 15 - Skeletal Muscle Function |date=2008-01-01 |url=https://www.sciencedirect.com/science/article/pii/B9780123704917000155 |work=Clinical Biochemistry of Domestic Animals (Sixth Edition) |pages=459–484 |editor-last=Kaneko |editor-first=J. Jerry |access-date=2023-10-10 |place=San Diego |publisher=Academic Press |isbn=978-0-12-370491-7 |editor2-last=Harvey |editor2-first=John W. |editor3-last=Bruss |editor3-first=Michael L.}}</ref>

: 2 ADP → ATP + AMP

Or AMP may be produced by the [[hydrolysis]] of one [[high energy phosphate]] bond of ADP:

: ADP  +  H<sub>2</sub>O → AMP + [[phosphate|P<sub>i</sub>]]

AMP can also be formed by hydrolysis of [[Adenosine triphosphate|ATP]] into AMP and [[pyrophosphate]]:

: ATP  +  H<sub>2</sub>O → AMP + [[pyrophosphate|PP<sub>i</sub>]]

When RNA is broken down by living systems, nucleoside monophosphates, including adenosine monophosphate, are formed.

AMP can be regenerated to ATP as follows:

: AMP + ATP → 2 ADP (adenylate kinase in the opposite direction)
: ADP + P<sub>i</sub> → ATP (this step is most often performed in aerobes by the [[ATP synthase]] during [[oxidative phosphorylation]])

AMP can be converted into [[inosine monophosphate]] by the [[enzyme]] [[myoadenylate deaminase]], freeing an [[ammonia]] group.

In a [[Catabolism|catabolic]] pathway, the [[purine nucleotide cycle]], adenosine monophosphate can be converted to [[uric acid]], which is excreted from the body in mammals.<ref>{{cite journal | vauthors = Maiuolo J, Oppedisano F, Gratteri S, Muscoli C, Mollace V | title = Regulation of uric acid metabolism and excretion | journal = International Journal of Cardiology | volume = 213 | pages = 8–14 | date = June 2016 | pmid = 26316329 | doi = 10.1016/j.ijcard.2015.08.109 | doi-access = free }}</ref>