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== Events == <onlyinclude> === By place === ==== Roman Empire ==== * [[February 28]] – [[Papyrus Oxyrhynchus 3035]], a warrant for the arrest of a Christian, is written.<ref>{{Cite web |date=2022-09-20 |title=P.Oxy. XLII 3035. Order to Arrest |url=https://portal.sds.ox.ac.uk/articles/online_resource/P_Oxy_XLII_3035_Order_to_Arrest/21166927/1 |access-date=2023-12-10 |website=figshare |language=en}}</ref> * The [[Goths]] invade [[Asia Minor]]. [[Dacia]] is lost for the [[Roman Empire]], and the Goths appear at the walls of [[Thessalonica]]. * The [[Franks]] cross the [[Rhine]]; the [[Alemanni]] reach [[Mediolanum]] ([[Milan]]) (disputed date). * In [[Africa (Roman province)|Africa]], the [[Berbers]] massacre Roman colonists. * King [[Shapur I]] of the [[Sasanian Empire]] invades [[Mesopotamia]] and [[Syria]]. He conquers and plunders [[Antioch]], destroys [[Dura-Europos]], and sacks the Anatolian city of [[Zeugma, Commagene|Zeugma]] on the [[Euphrates]].<ref>{{Cite web |title=Zeugma |url=https://www.historyhit.com/locations/zeugma/ |access-date=2023-12-10 |website=History Hit |language=en-GB}}</ref> A devastating fire and an earthquake soon follow, causing Zeugma to be abandoned. * Cities in the Roman Empire begin to build walls, as the defense of the frontiers begins to crumble; future emperor [[Aurelian]] inspects along the Rhine. ==== Asia ==== * Peace and unity are finally restored in China, with the victories of the [[Cao Wei|Wei Kingdom]] in the north. The ruling dynasty is worn out by war, and the kingdom is ruled by ministers on their behalf. === By topic === ==== Medicine ==== * The great [[pandemic]] of the Roman world strikes violently in [[Pontus (region)|Pontus]] on the [[Black Sea]], and causes enormous loss of life in [[Alexandria]], encouraging thousands to embrace Christianity. ==== Religion ==== * Emperor [[Valerian (emperor)|Valerian]] persecutes Christians. * [[Pope Stephen I]] threatens to excommunicate [[Cyprian]], bishop of [[Carthage]], and other [[bishop]]s in Africa and Asia Minor, unless they stop rebaptizing [[heresy|heretics]]. Cyprian attacks the Pope in a treatise that gains support from the [[Council of Carthage (256)|Council of Carthage]]. He sends envoys to [[Ancient Rome|Rome]], raising the specter of a [[schism]] between the Roman and Carthaginian [[Church (building)|Church]]es. * A [[Synod of Carthage (256)|Synod of Carthage]] is held. </onlyinclude>
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